T1D can be prevented and will never threaten anyone again

Imagine a future where a universal vaccine for type 1 diabetes (T1D) exists and no one needs to worry about getting T1D.

Why it matters

T1D is a chronic, life-threatening autoimmune disease that is currently not preventable. Eighty-five percent of people who develop it have no family history of the disease, and epidemiologists predict a threefold increase in the number of young people who have T1D by 2050.

At JDRF, we want to change that outlook and make it possible that no one ever again develops T1D. The ultimate aim of our Prevention Program is creating a childhood vaccine to immunize against the causes of T1D. While we work toward that goal, we also are committed to stopping the progression of T1D once it’s begun so we can prevent dependency on insulin therapy.

Our pioneering research

JDRF-funded research has identified a number of potential triggers associated with the onset of T1D, including viruses and environmental conditions. These discoveries could point to ways of developing vaccines that will stop the triggers and prevent autoimmune attacks on the body’s insulin-producing cells.

We’re pursuing a number of promising approaches to prevention, including therapies that prevent or reverse specific gut bacteria changes that have been associated with the development of T1D.


JDRF scientists

Meet the experts leading prevention research.

  • Jessica L. Dunne, Ph.D.

    Jessica L. Dunne, Ph.D.

    Jessica L. Dunne is director of discovery research for the JDRF Prevention Program, which focuses on delaying or preventing the onset of symptomatic T1D.

    Jessica L. Dunne, Ph.D.

  • Sanjoy Dutta, Ph.D.

    Sanjoy Dutta, Ph.D.

    Sanjoy Dutta is associate vice president, translational development for JDRF, where he focuses on managing and developing glucose control research.

    Sanjoy Dutta, Ph.D.

Explore more life-changing research

Find out why each of these research areas is part of the plan for a world without T1D.