Innovative Grants/Pilot and Research Tool Grants

Summary

Description Innovative: supports proposals for highly innovative research with significant potential to accelerate the mission of JDRF. The innovative research should have the potential for a change in the current paradigm or conventional wisdom or to lead to a seminal discovery or to be groundbreaking.Pilot and Research Tool: supports innovative pilot studies with limited, well-defined objectives.  Pilot studies should be designed to answer a single, clear, question of high potential impact.  Research Tool grants are meant to support the creation of critical research tools where none currently exist or where the existing tools are demonstrably inadequate.  The resulting reagents must be made readily available to the broader research community.
Institutional Eligibility Domestic & foreign non-profit organizations; public & private universities, colleges, hospitals, & laboratories; units of state and local governments; eligible agencies of the federal government
Applicant Eligibility Required: MD, DMD, DVM, PhD or equivalent and faculty position or equivalent
Proposal
JDRF is transitioning to a new online Research Management System called RMS360 in the spring and summer of 2013. Beginning May 20, 2013, researchers can register in RMS360. Beginning July 1, 2013 all proposal details and templates will be available to researchers in RMS360. The proposal deadline is August 30, 2013.
Applicant Checklist Please use the Innovative Grants/Pilot and Research Tool Grant Applicant Checklist as a summary of information we will require for complete submission of a full proposal in addition to the below information. Note that JDRF will provide all proposal details and templates in RMS360 starting on July 1, 2013.
Terms Innovative: 110,000 USD maximum/year for one year, including up to 10% for indirect costsPilot and Research Tool: 75,000 USD maximum/year for one year, including up to 10% for indirect costs
Upcoming Deadline See Grant Opportunities and Deadlines

Description

JDRF provides seed funding for highly innovative research with significant potential to accelerate the mission of JDRF. The innovative research should have the potential for a change in the current paradigm or conventional wisdom or to lead to a seminal discovery or to be groundbreaking. Preliminary data is not required in the proposal but the underlying premise, goal, or hypothesis must be plausible and the proposal must be focused with a well-defined goal.

Through “pilot grants” JDRF will now provide specific funding to answer a critical question of limited scope that would not normally be considered competitive for innovative funding.  For example a “single experiment” or otherwise narrowly defined question, whose answer could provide the rationale for a more extensive investigation would be considered for funding under this grant type.

Through “research tool grants” JDRF will provide funding for the generation of a critical research reagent where none currently exists or where existing reagents are demonstrably inadequate.  The applicant should provide a clear rationale supporting both the need for the reagent and its potential to affect research in T1D.  Any reagents generated must be made readily available to the research community.

Eligibility

Proposals may be submitted by domestic and foreign non-profit organizations, public and private, such as universities, colleges, hospitals, laboratories, units of state and local governments, and eligible agencies of the federal government. Innovative (but not pilot and research tool) proposals from for-profit organizations will also be considered. Applicants must hold an M.D., D.M.D., D.V.M., Ph.D., or equivalent and have a faculty position or equivalent at a college, university, medical school, or other research facility. There are no citizenship requirements for this program. To assure continued excellence and diversity among applicants and awardees, JDRF welcomes proposals from all qualified individuals and encourages proposals from persons with disabilities, women, and members of minority groups underrepresented in the sciences.

Proposal

JDRF is transitioning to a new online Research Management System called RMS360 in the spring and summer of 2013. Beginning May 20, 2013, researchers can register in RMS360. Beginning July 1, 2013 all proposal details and templates will be available to researchers in RMS360. The proposal deadline is August 30, 2013.

Please use the Innovative Grants/Pilot and Research Tool Grant Applicant Checklist as a summary of information we will require for complete submission of a full proposal. Note that JDRF will provide all proposal details and templates in RMS360 on July 1, 2013.

Research Plan (template available on July 1, 2013)

The research plan may not exceed 3 pages, including figures and tables, but not including references. The research plan must be organized as follows: a) Specific Aims; b) Background and Significance to Type 1 Diabetes (the rationale supporting “research tool” grants should be provided in this section); c) Preliminary Studies (if available); d) Research Design and Methods; e) Literature Cited (no page limit). Note: For a project proposing Human Subject Research, please review the Human Subject Research Guidelines.

Evaluation

Proposals will be evaluated in accordance with the criteria described below. Evaluations will be competitive and performed by an appropriate review panel convened by JDRF the review criteria include:

    1. Innovation, potential impact, and relevance to JDRF goals
    2. Feasibility of experimental approach and completing in one year
    3. Clarity of proposed objectives
    4. Qualifications and research experience of the principal investigators and collaborators
    5. Availability of resources and facilities necessary for the project
    6. Appropriateness of the proposed budget in relation to the proposed research
    7. For “Research Tool” proposals only; demonstrable need for the novel reagents/tools

Terms of the Award

Innovative grants provide one year of support for a maximum of USD 100,000 in direct costs and indirect costs of 10%, for a total of USD 110,000. Pilot and Research Tool grants provide up to one year of support for a maximum of USD 75,000 including indirect costs (which may not exceed 10% of the total amount requested).  These grants are not renewable. A final progress report is due within 75 days following the close of the award.

Innovative proposals with significantly higher cost or requiring greater than one year of funding may still be considered for an Innovative Grant at the discretion of JDRF scientists. If you believe that your Innovative project requires a greater budget or funding period, please contact JDRF Program Scientists in the relevant area to discuss possible options for submission. Note: Pilot and Research Tool proposals are limited to a maximum amount of $75,000.
Examples of innovative proposals that might be considered as exceptions include:

    • Research that requires collaborative or multi-disciplinary approaches to address a single hypothesis
    • Research that requires high-cost resources, e.g. costly reagents for genomics/ proteomics studies
    • Studies that employ large-animal models or animal models that require lengthy development or distant endpoints