A Picture’s Worth a Thousand Words

JDRF-Funded Study Shows New Imaging Technique Can Track Beta Cell Status For nearly 100 years, we have known that type 1 diabetes (T1D) is a disease fundamentally about the progressive loss of insulin-producing beta cells, but measuring that loss has continued to elude researchers—at least until now. In a recent scientific publication, JDRF-funded researchers used […]

Specific Protein May Help Beta Cells Survive in Type 1 Diabetes

JDRF-funded researchers find therapeutic potential of MANF protein to reduce beta cell stress in type 1 diabetes. In the healthy pancreas of someone without type 1 diabetes (T1D), the hormone insulin (essential for turning food into energy) is produced, stored, and released in a normal “factory-like” process within pancreatic beta cells in response to glucose […]

A Well-Known Hormone Turns On Beta Cell Survival Genes

A hormone called GLP-1 has long been thought to have a positive impact on beta cell survival, and now scientists have started to uncover how it works. The new findings provide scientists with insights to improve the effects of currently available drugs that may prevent beta cell loss and promote beta cell survival in people with T1D or in those in the transplant setting.

Key Enzyme Boosts Beta Cell Numbers

JDRF-funded researchers have identified a key signal that prompts existing beta cells, the only cells in the body that produce the hormone insulin, to form new beta cells. Their breakthrough discovery may ultimately be used to develop new treatments that will help to increase the number or function of beta cells in people with type […]