A Father’s Formula

“How is managing diabetes like navigating an airplane?” That may sound like the beginning of a bad joke, but the answer resulted in a promising innovation in T1D treatment in JDRF’s current research portfolio. Like many other parents of children with type 1 diabetes (T1D), Don Matheson is well versed in the latest research advances […]

Top Research Highlights

Every day, JDRF leverages the expertise and innovation of distinguished researchers from across the globe to support research for life-changing treatments and ultimately a cure for type 1 diabetes (T1D). Our mission aims to serve everybody with T1D—at all ages and stages of the disease. Please enjoy reading about some of the most recent advances […]

FDA Issues Final Artificial Pancreas Guidance

The U.S. Food and Drug Administration (FDA) announced on November 9 the issuance of its final guidance for the development of artificial pancreas systems. The guidance incorporates nearly all of JDRF’s recommendations. This news represents a milestone victory for JDRF and the type 1 diabetes (T1D) community, as the technology is viewed by medical experts […]

Progress in Testing Artificial Pancreas Systems in Clinical and Real-World Settings

A first-of-its-kind clinical pilot study has demonstrated the safety and feasibility of an artificial pancreas system in an outpatient, “real-world” setting. A second clinical study has shown that a hypoglycemia-hyperglycemia minimizer system can predict when blood-glucose levels are about to rise or fall and make appropriate adjustments in insulin delivery. These JDRF-supported studies represent critical steps on the path to a functional artificial pancreas for the benefit of people living with T1D.

Researchers Formulate Stable Liquid Glucagon

JDRF-funded researchers have developed a formulation of liquid glucagon that remains stable and viable for long periods of time and thus may be usable in standard diabetes pumps. The research represents advancement toward the routine delivery of glucagon for people with T1D and may also facilitate the development of bihormonal closed-loop artificial pancreas systems.

JDRF Partners With Dexcom to Support the Manufacture of a Smart Transmitter Prototype for Artificial Pancreas Research

JDRF has partnered with San Diego–based medical company Dexcom, Inc. to support the manufacture of a so-called smart transmitter prototype, which will be available for research purposes before it will be commercially available. The technological advance not only would reduce the number of devices a person would have to wear with an artificial pancreas system, but would also enable wireless connectivity among these devices—an important feature that would give people with T1D the freedom of movement while participating in real-life outpatient studies.

JDRF Encouraged by FDA Draft Guidance for Artificial Pancreas

The JDRF Artificial Pancreas Project has significantly accelerated progress toward the delivery of the first artificial pancreas (AP) systems to people with diabetes. Research progress has been exceptional with multiple studies in controlled settings demonstrating that AP systems can significantly reduce high and low blood sugar levels automatically. For people with diabetes to realize the […]

Taking the Artificial Pancreas Out for a Walk

The closed-loop artificial pancreas, which combines an insulin pump with a glucose monitor, has been successfully tested on people in controlled hospital settings. Now, researchers believe that it is time to try this innovation in real-life environments. Last summer, JDRF formed a panel of experts to provide advice about how to bring this technology out […]

JDRF Works to Speed Delivery of Faster-Acting Insulin

In another key step forward on the road to an artificial pancreas, JDRF has launched a research program to speed the development of faster-acting insulin. Through the initiative, JDRF is funding investigators at leading academic institutions to test novel insulin formulations and delivery systems. The goal is to develop faster-acting insulin for use in an […]