FDA Issues Final Artificial Pancreas Guidance

The U.S. Food and Drug Administration (FDA) announced on November 9 the issuance of its final guidance for the development of artificial pancreas systems. The guidance incorporates nearly all of JDRF’s recommendations. This news represents a milestone victory for JDRF and the type 1 diabetes (T1D) community, as the technology is viewed by medical experts […]

Progress in Testing Artificial Pancreas Systems in Clinical and Real-World Settings

A first-of-its-kind clinical pilot study has demonstrated the safety and feasibility of an artificial pancreas system in an outpatient, “real-world” setting. A second clinical study has shown that a hypoglycemia-hyperglycemia minimizer system can predict when blood-glucose levels are about to rise or fall and make appropriate adjustments in insulin delivery. These JDRF-supported studies represent critical steps on the path to a functional artificial pancreas for the benefit of people living with T1D.

Researchers Formulate Stable Liquid Glucagon

JDRF-funded researchers have developed a formulation of liquid glucagon that remains stable and viable for long periods of time and thus may be usable in standard diabetes pumps. The research represents advancement toward the routine delivery of glucagon for people with T1D and may also facilitate the development of bihormonal closed-loop artificial pancreas systems.

JDRF Partners With Dexcom to Support the Manufacture of a Smart Transmitter Prototype for Artificial Pancreas Research

JDRF has partnered with San Diego–based medical company Dexcom, Inc. to support the manufacture of a so-called smart transmitter prototype, which will be available for research purposes before it will be commercially available. The technological advance not only would reduce the number of devices a person would have to wear with an artificial pancreas system, but would also enable wireless connectivity among these devices—an important feature that would give people with T1D the freedom of movement while participating in real-life outpatient studies.

JDRF Encouraged by FDA Draft Guidance for Artificial Pancreas

The JDRF Artificial Pancreas Project has significantly accelerated progress toward the delivery of the first artificial pancreas (AP) systems to people with diabetes. Research progress has been exceptional with multiple studies in controlled settings demonstrating that AP systems can significantly reduce high and low blood sugar levels automatically. For people with diabetes to realize the […]

Taking the Artificial Pancreas Out for a Walk

The closed-loop artificial pancreas, which combines an insulin pump with a glucose monitor, has been successfully tested on people in controlled hospital settings. Now, researchers believe that it is time to try this innovation in real-life environments. Last summer, JDRF formed a panel of experts to provide advice about how to bring this technology out […]

JDRF Works to Speed Delivery of Faster-Acting Insulin

In another key step forward on the road to an artificial pancreas, JDRF has launched a research program to speed the development of faster-acting insulin. Through the initiative, JDRF is funding investigators at leading academic institutions to test novel insulin formulations and delivery systems. The goal is to develop faster-acting insulin for use in an […]

Partnerships and Progress Toward an Artificial Pancreas

These developments represent a giant step forward on the path to achieving an artificial pancreas, a fully automated system that can dispense insulin to patients based on real-time changes in blood sugar levels. Even the earliest systems could bring dramatic changes in the quality of life for people with type 1 diabetes.

Four Separate Publications Document the Benefits of CGM

Continuous glucose monitors are more than simply devices of convenience for people with diabetes—they are tools that can substantially improve blood sugar control in people of all ages when used regularly, without increasing the risk of dangerous low blood sugar. The growing evidence of the benefits of CGM underscores the importance of continued research into a closed-loop artificial pancreas, a system that uses CGM data to automatically deliver the right amount of insulin through a pump.