A Difficult Journey from the Lab to People with Type 1 Diabetes

New study highlights the challenges of translating promising research to effective treatments Results from a clinical study in people with type 1 diabetes (T1D) who were treated with a combination of two drugs in an attempt to improve their beta cell survival and stimulate beta cell regeneration are so far inconclusive. The study, called REPAIR-T1D […]

Top 10 Advances in T1D Research

JDRF-supported progress in fiscal year 2014 JDRF sets ambitious goals for progress in type 1 diabetes (T1D) research each year because our supporters inspire us to aim higher. We invite you to read about the real impact our strategic plan is making and hope you are as inspired as we are as each of these […]

Next-Generation Artificial Pancreas System Gears Up for Test Drive

Pilot study will evaluate advanced artificial pancreas technology under real-world situations For several years, JDRF-funded researchers at the University of Virginia Center for Diabetes Technology have been hard at work designing an artificial pancreas system that would allow individuals with type 1 diabetes (T1D) to go about their daily lives and sleep through the night […]

JDRF Ranked as Top Non-Governmental Diabetes Research Funder

Independent analysis of key scientific literature found JDRF among the top organizations funding diabetes research globally In a recent independent analysis of key diabetes-related scientific literature, JDRF was ranked as the third most frequently cited funder of diabetes research globally, behind only the U.S. National Institutes of Health and the National Natural Science Foundation of […]

A Picture’s Worth a Thousand Words

JDRF-Funded Study Shows New Imaging Technique Can Track Beta Cell Status For nearly 100 years, we have known that type 1 diabetes (T1D) is a disease fundamentally about the progressive loss of insulin-producing beta cells, but measuring that loss has continued to elude researchers—at least until now. In a recent scientific publication, JDRF-funded researchers used […]

Specific Protein May Help Beta Cells Survive in Type 1 Diabetes

JDRF-funded researchers find therapeutic potential of MANF protein to reduce beta cell stress in type 1 diabetes. In the healthy pancreas of someone without type 1 diabetes (T1D), the hormone insulin (essential for turning food into energy) is produced, stored, and released in a normal “factory-like” process within pancreatic beta cells in response to glucose […]

Sleeping Without Fear

Study: Artificial pancreas systems with predictive low-glucose-suspend help reduce overnight hypoglycemia in individuals with type 1 diabetes Bedtime may soon be safer and a lot less anxiety filled for people with type 1 diabetes (T1D) thanks to software being developed as a next-step component for artificial pancreas systems. Called predictive low-glucose-suspend (pLGS), it interacts with […]

Hope for kidney health in gout drug

PERL study will explore the potential of allopurinol to delay or halt kidney disease in people with type 1 diabetes. As we near the end of March, National Kidney Month, we find ourselves at the beginning stages of an exciting new clinical trial that could lead to better health for people with type 1 diabetes […]

Merck smart insulin project advancing into clinical trials

On May 6, 2014, Merck held an investor briefing and provided updates on various strategic initiatives, including its smart insulin project acquired in 2010 when it purchased SmartCells. SmartCells — a diabetes drug-development company that received early support from JDRF — was founded in 2003 by Todd Zion, Ph.D., an MIT chemical engineer who had […]

Redefining the Diagnosis of Type 1 Diabetes

Updated criteria could open new possibilities for intervention before symptoms appear JDRF is leading a pertinent discussion in the diabetes field about what defines a diagnosis of type 1 diabetes (T1D). At the 14th Annual Rachmiel Levine Diabetes and Obesity Symposium today, Richard Insel, M.D., JDRF’s chief scientific officer, reviewed evidence supporting the need to […]