Researchers recently demonstrated for the first time a direct association between human beta cell destruction and CD8 T cells, which are cells that play an important role in the body’s immune system. This autoimmune “attack” is a hallmark of T1D and it results in the destruction of insulin-producing beta cells in the pancreas. In their investigation, the researchers used human tissue samples from the pancreases of T1D organ donors obtained through nPOD, a JDRF collaborative research project. This new study provides evidence that CD8 T cells are present in the islets of the pancreas that contain beta cells. These findings are important for future research on preserving beta-cell function and establishing biomarkers for therapies for T1D.
My nine-year-old daughter was diagnosed with type 1 diabetes (T1D) five days ago. We are a military family currently stationed in South Korea. We are with very few English resources in the area. It looks like we will get an emergency move to our next duty station in El Paso, TX, in a couple of weeks. How do we find quality care in a foreign country, manage an international move with a child with T1D, and find quality care to deal with a new diagnosis?
Season’s greetings to all! Our December issue of Countdown, JDRF’s leading publication, brings you an abundance of research and advocacy news, and photos from some of our most recent events from coast to coast and across the globe. You’ll read about how JDRF is making great strides in better treatments, prevention, and a cure for […]
JDRF and the Leona M. and Harry B. Helmsley Charitable Trust, two of the largest non-government funders of type 1 diabetes (T1D) programs, teamed up in November to optimize their common efforts to improve the health of people living with the disease. Since 2007, the Leona M. and Harry B. Helmsley Charitable Trust has provided […]
Question: I am an adult with type 1 diabetes and will be traveling alone by plane at the end of the summer. I have an insulin pump, needles and syringes, and other supplies. Do I have to have a physician’s note with me when I go through airport security? And can I go through the […]
This year marks JDRF’s seventh Children’s Congress. I find it inspiring that the very idea for Children’s Congress came from a child with type 1 diabetes. In 1999, eight-year-old Tommy Solo of Massachusetts heard his mother talking to a group of adults about going to Washington, D.C., to petition Congress for more funding for type […]
The success of the JDRF Children’s Congress is significantly strengthened by a unique collaboration between JDRF advocates, government representatives, and corporate sponsors who combine their resources and their voices to keep type 1 diabetes research moving forward. At the Corporate Partner Recognition Luncheon on June 21, JDRF leadership and delegates recognized two 2011 Children’s Congress […]
Welcome to Countdown! For all of us connected to type 1 diabetes—adults and children and their families, physicians, researchers, everyone at JDRF—we are living in exciting times! In the past eight years that I have been at JDRF, I have seen significant advances in type 1 diabetes discovery research and its clinical translation, and […]
By Richard Insel, M.D. As JDRF remains steadfast in its mission of curing type 1 diabetes, we are also committed to both improving treatments for individuals with the disease and preventing the disorder itself. Our treatment priorities include developing new drugs and devices that significantly improve glucose control, reduce the daily burden of living with […]
Alpha-to-beta cell conversion or “reprogramming” is an early, but promising, therapeutic strategy for T1D. Scientists have now shown that the body can function normally without most of its alpha cells, addressing a potential safety concern for alpha-to-beta cell conversion.